Comparison of Postoperative Anal Function Between Different Anastomosis Techniques(Parks Versus Bacon) in Low Rectal Cancer: A Prospective, Multicentric and Randomized Controlled Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to compare the postoperative anal function of patients with ultra-low rectal cancer after Parks operation (colon anal anastomosis) and Bacon operation (colon anal pull-out anastomosis), which may provide clinical evidence for the improvement of anal function and quality of life. The main questions it aims to answer are: the difference of anal function 1 year after surgery type of study: clinical trial participant population: patients with low rectal cancer Participants will receive Parks operation of Bacon operation If there is a comparison group: Researchers will compare Parks and Bacon operation to see if the anal function 1 year after surgery is different.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Men or women, aged between 18 and 75 years;

• Pathological diagnosis of rectal cancer before operation, with the distance from the lower edge of the tumor to the dentate line ≤ 3cm by MR imaging;

• No local complications (including complete/ incomplete obstruction, active bleeding, local invasion of sphincter or levator ani, etc.) before operation;

• Suitable for anal preservation surgery discussed by MDT;

• Adequate bone marrow, liver, renal and cardiac function meeting the requirements of surgery and anesthesia;

• R0 resection is expected technically;

• Provision of written informed consent.

Locations
Other Locations
China
The Sixth Affiliated Hospital, Sun Yatsen University
RECRUITING
Guangzhou
Contact Information
Primary
Jun Huang, MD
huangj97@mail.sysu.edu.cn
13926451242
Time Frame
Start Date: 2023-08-08
Estimated Completion Date: 2027-08-08
Participants
Target number of participants: 256
Treatments
Active_comparator: Parks technique
patients receive coloanal anastomosis operation
Experimental: Bacon technique
patients receive coloanal pull-out anastomosis operation
Related Therapeutic Areas
Sponsors
Leads: Sixth Affiliated Hospital, Sun Yat-sen University

This content was sourced from clinicaltrials.gov